Department of Surgery

Previous Years - Simmons' Surgery Research Day

2017

Fifteenth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day

Wednesday May 10, 2017


Keynote Lecture: "Gut Integrity In Sepsis" 

Craig M. Coopersmith, MD, FACS, FCCM, Professor & Vice Chair, Surgery, Emory University School of Medicine; Director, 5E Surgical ICU; Associate Director, Emory Critical Care Center


Program and Schedule (PDF)


Oral Presentation Award Winners

  • First Place: Jennifer L. Miller-Ocuin, MD, “Inhibition of Autophagy Improves Pathologic and Biomarker Response to Pre-Operative Gemcitabine/Nab-Paclitaxel in Potentially Resectable Pancreatic Cancer: A Phase II Randomized Controlled Trial”

Runners-up:

  • Joshua Brown, MD, MSc, “Speed Isn’t Everything: Identifying Patients Who May Benefit from Helicopter Transport Despite Faster Ground Transport”
  • Mitch Dyer, MD, “Platelet-Derived HMGB1 Promotes DVT Formation via Neutrophil Extracellular Traps”
  • Katie Sun, PhD, “Cardiolipin Functions as Intracellular DAMP to Activate Caspase 11 After Hemorrhagic Shock”

Poster Presentation Award Winners

  • Daniel Brown (Epidemiology/Outcomes)
  • Shaun Siow, MD (Quality Improvement)
  • Vikas Sud (Basic Science)
  • Joseph Fusco (Basic & Translational Sciences)

View photos

2016

Fourteenth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day

Wednesday, May 11, 2016


Keynote Lecture: "Trauma Care: A Case Study in Translating Research into Policy"

Avery B. Nathens, MD, PhD, FRCS(C), Surgeon-in-Chief, Sunnybrook Health Sciences Center; Professor of Surgery, University of Toronto; DeSouza Chair in Trauma Research


Program and Schedule (PDF)


Oral Presentation Award Winners

  • First Place: Mitchell Dyer, MD, “Improved Hemostasis Following Trauma Using Platelet-mimicking Intravenous Synthetic Hemostat Nanotechnology “

Runners-up:

  • Samer Tohme, MD, “Hypoxia Mediates Mitochondrial Biogenesis in Hepatocellular Carcinoma to Promote Tumor Growth via HMGB1 and TLR9 Interaction”
  • Jennifer Miller, MD, “PAD4-Mediated NETosis Leads to Increased Carcinogenesis in Murine Pancreatic Cancer Models through an HMGB1-Dependent Mechanism”

Poster Presentation Award Winners

  • Xianghong Zhang, MD, "CaMKI Regulates Mitophagy through PINK1/Parkin during Sepsis"
  • Joshua Brown, MD, "Comparing the Air Medical Prehospital Triage Score to Current Practice for Helicopter Triage of Trauma Patients: A Cost-effectiveness Analysis" 
  • Patrick Varley, MD, "Utility of Lymph Node Yield as a Quality Metric for Node-negative Pancreatic Head Adenocarcinoma"

View photos

2015

Thirteenth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day

Wednesday, May 13, 2015


Keynote Lecture: “The Challenges and Rewards of Translational Research - One Surgeon's Journey”

Melina R. Kibbe, MD, FACS, FAHA, Professor and Vice Chair of Research; Edward G. Elcock Professor of Surgical Research, Department of Surgery, Northwestern University


Program and Schedule (PDF)


Oral Presentation Award Winners

  • First Place: Michal Radomski, MD, "Complement Inhibition Enhances the Therapeutic Efficacy of an Oncolytic Vaccinia Virus"

Runners Up:

  • Kellie Cunningham, MD, "Peroxisome Proliferator-activated Receptor g Coactivator 1α (PGC1α) Helps Maintain the Intestinal Barrier and Protect against Inflammation in Experimental Colitis"
  • Samer Tohme, "The Role of Neutrophil Extracellular Traps in Promoting Metastatic Cancer Following Surgical Stress"

Poster Presentation Award Winners

  • Stephanie Downs-Canner, "The Tumor-Driven Conversion of TH17 cells into Tregs"
  • Hai Huang, "DAMPs-activated Neutrophil Extracellular Trap Exacerbates Sterile Inflammatory Liver Injury"
  • Patrick Varley, "Unexplained Heterogeneity in Late Survival for Early Stage Pancreatic Cancer"

View photos

2014

Twelfth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day

Wednesday, May 14, 2014


Keynote Lecture: “Small Molecules for Small Patients: A Surgical Journey into the Pathogenesis and Treatment of Necrotizing Enterocolitis”

David J. Hackman, MD, PhD, FACS, Watson Family Professor of Surgery; Associate Dean for Medical Student Research; Professor of Surgery and Cell Biology and Physiology, University of Pittsburgh School of Medicine; Co-director, Fetal Diagnosis and Treatment Center, Children’s Hospital of Pittsburgh of UPMC


Program and Schedule (PDF)


Oral Presentation Award Winners

  • First Place: Brian Boone, MD, "Neutrophil Autophagy Promotes Neutrophil Extracellular Traps (NET) in Pancreatic Adenocarcinoma Contributing to Tumor Growth and Metastases"

Runners up:

  • Qian "Katie" Sun, MD, PhD, "HMGB1 Protects Hepatocytes from Cell Death by Activating Caspase-1 and Up-Regulating Autophagy after Redox Stress"
  • Shahab Shaffiey, MD, "Generation of an Artificial Intestine and Validation in a Dog Model"

Poster Presentation Award Winners

  • Khalid Almahmoud, "Impact of Severity on Dynamic Inflammation Networks Following Blunt Trauma"
  • Mostafa Ramadan, "B cells play an organ protective role in Trauma + Hemorrhagic Shock"
  • Alexandra Dreyzin, "Long-Term Outcomes and Predictors in Pediatric Liver Re-Transplantation"
  • Hongpeng Jia, "Deletion of HMGB1 from the Intestinal Epithelium Exacerbates Experimental Necrotizing Enterocolitis in the Newborn Gut but Protects the Lung from Inflammation"

View photos

2013

Eleventh Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: “Regenerative Medicine: Current Concepts in Pancreatic Cancer”

Anthony Atala, MD, Director, Wake Forest Institute for Regenerative Medicine; W.H. Boyce Professor and Chair, Department of Urology Wake Forest School of Medicine


Oral Presentation Award Winners

  • First Place: Yousef El-Gohary, MA, MD, MRCS, "Direct Evidence that Pancreatic Ducts are a Source for New Beta Cells during the Juvenile Period and During Regeneration”

Runners up:

  • Kent Zettel, MD, “DC Play an Unexpected Role in TLR4 Dependent Inflammation and Organ Damage Following Hemorrhagic Shock with Tissue Trauma”
  • Rami Namas, MD, MRCS, “Circulating Biomarker Networks Differentiate Susceptibility to Infection Following Trauma in Humans”

Poster Presentation Award Winners

  • Sean Whelan, "Lipopolysaccharide Induced Autophagy and Mitochondrial Biogenesis in Hepatocytes/Liver are Dependent on Mitochondrial Reactive Oxygen Species, Nrf-2 Signaling"
  • Rob Klune, IL-23 Activation of NKT Cells Contributes to Early Damage Following Hepatic I/R Injury"
  • Shahab Shaffiey, "In Vitro and In Vivo Growth of Intestinal Stem Cells using a Novel Scaffold"

     

2012

Tenth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "Advancing Translational Research in Pancreatic Cancer"

Diane M. Simeone, MD, Lazar J. Greenfield Professor of Surgery; Molecular and Integrative Physiology Chief, Division of HPB and Advanced Gastrointestinal Surgery, University of Michigan Healthy System

2011

Ninth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "Memory, Surgery, and Surgical Research"

Daniel R. Meldrum, MD, FACS, FAHA, Professor of Surgery and Physiology, Section of Cardiothoracic Surgery, Indiana University School of Medicine

2010

Eighth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "Enhancing Vein Graft Patency: From the Molecular to the Obvious"

Colleen M. Brophy, MD, Professor of Surgery, Division of Vascular Surgery, Vanderbilt University

2009

Seventh Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "Liver Translational Research: The Bench Work Does Matter"

David A. Geller, MD, Professor of Surgery; Codirector, UPMC Liver Cancer Center, University of Pittsburgh

2008

Sixth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "VEGF and VEGF Receptors in CRC: Beyond Angiogenesis"

Lee M. Ellis, MD, FACS, Professor of Surgery and Cancer Biology; William C. Liedtke Jr. Chair in Cancer Research; Chair, Ad Interim, Department of Cancer Biology, University of Texas MD Anderson Cancer Center

2007

Fifth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "How Microbial Pathogens Sense Host Stress and Respond Accordingly"

John C. Alverdy, MD, FACS, Professor of Surgery; Director, Minimally Invasive/Bariatric Surgery, University of Chicago

2006

Fourth Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: Reparative and Regenerative Medicine: A Surgeon's Perspective"

Michael T. Longaker, MD, MBA, FACS, Deane P. and Louise Mitchell Professor; Director, Children's Surgical Research Program; Deputy Director, Institute of Stem Cell Biology and Regenerative Medicine; Director, Program in Regenerative Medicine, Stanford University School of Medicine

2005

Third Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "Why Are You Killing My Patient?"

Michael B. Yaffe, MD, PhD, Associate Professor of Biology, Massachusetts Institute of Technology

2004

Second Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "The Inflammatory Reflex"

Kevin J. Tracey, MD, Professor and Director, Center for Patient-Oriented Research; Program Director, General Clinical Research Center, North Shore-LIJ Research Institute

2003

First Annual Richard L. Simmons Lecture in Surgical Science and Department of Surgery Research Day


Keynote Lecture: "Hyperosmolar Solutions for Fluid Resuscitation during Critical Illness"

Ori D. Rotstein, MD, Professor of Surgery, Department of Surgery, University of Toronto